Stefano Di Santo, PhD

Post-Doctoral Fellow

Languages: German, English

Contact

Social Media

All Publications

  1. Kissling C, Di Santo S. ‌Tumor Treating Fields – Behind and Beyond Inhibiting the Cancer Cell Cycle. CNS Neurol Disord Drug Targets. 2020 Jul 2.
  2. Di Santo S, Widmer H. ‌Paracrine factors for neurodegenerative disorders: special emphasis on Parkinson's disease Neural Regen Res. 2016 Apr;11(4):570-1.
  3. Bitterli L, Afan S, Bühler S, Di Santo S, Zwahlen M, Schmidlin K, Yang Z, Baumgartner I, Diehm N, Kalka C. ‌Endothelial progenitor cells as a biological marker of peripheral artery disease Vasc Med. 2016 Feb;21(1):3-11.
  4. Seiler S, Di Santo S, Widmer H. ‌Non-canonical actions of Nogo-A and its receptors Biochem Pharmacol. 2016 Jan 15;100:28-39.
  5. Di Santo S, Fuchs A, Periasamy R, Seiler S, Widmer H. ‌The Cytoprotective Effects of Human Endothelial Progenitor Cell-Conditioned Medium against an Ischemic Insult Are Not Dependent on VEGF and IL-8 Cell Transplant . 2016;25(4):735-47.
  6. Seiler S, Di Santo S, Widmer H. ‌ Nogo-A Neutralization Improves Graft Function in a Rat Model of Parkinson’s Disease Front Cell Neurosci. 2016 Apr 5;10:87.
  7. Schawkat K, Di Santo S, Seiler S, Ducray A, Widmer H. ‌Loss of Nogo-A-expressing neurons in a rat model of Parkinson’s disease Neuroscience. 2015 Mar 12;288:59-72.
  8. Liechti R, Ducray A, Jensen P, Di Santo S, Seiler S, Jensen C, Meyer M, Widmer H. ‌Characterization of fetal antigen 1/delta-like 1 homologue expressing cells in the rat nigrostriatal system: effects of a unilateral 6-hydroxydopamine lesion PLoS One. 2015 Feb 27;10(2):e0116088.
  9. Di Santo S, Mina A, Ducray A, Widmer H, Senn P. ‌Creatine supports propagation and promotes neuronal differentiation of inner ear progenitor cells Neuroreport. 2014 May 7;25(7):446-51.
  10. Di Santo S, Seiler S, Fuchs A, Staudigl J, Widmer H. ‌The Secretome of Endothelial Progenitor Cells Promotes Brain Endothelial Cell Activity through PI3-Kinase and MAP-Kinase PLoS One. 2014 Apr 22;9(4):e95731.
Show more
  1. Seiler S, Pollini D, Di Santo S, Widmer H. ‌Antagonizing Nogo-receptor 1 promotes the number of cultured dopaminergic neurons and elongates their neurites Neuroreport. 2013 Dec 18;24(18):1047-52.
  2. Ortmann J, Veit M, Zingg S, Di Santo S, Traupe T, Yang Z, Völzmann J, Dubey R, Christen S, Baumgartner I. ‌Estrogen Receptor-α But Not -β or GPER Inhibits High Glucose-Induced Human VSMC Proliferation: Potential Role of ROS and ERK J Clin Endocrinol Metab. 2011 Jan;96(1):220-8.
  3. Ortmann J, Veit M, Zingg S, Di Santo S, Traupe T, Yang Z, Völzmann J, Dubey R, Christen S, Baumgartner I. ‌Estrogen Receptor-α But Not -β or GPER Inhibits High Glucose-Induced Human VSMC Proliferation: Potential Role of ROS and ERK J Clin Endocrinol Metab. 2011 Jan;96(1):220-8.
  4. Di Santo S, Seiler S, Ducray A, Meyer M, Widmer H. ‌A Subpopulation of Dopaminergic Neurons Coexpresses Serotonin in Ventral Mesencephalic Cultures but not after Intrastriatal Transplantation in a Rat Model of Parkinson's Disease Cell Transplant. 2017 Apr 13;26(4):679-691.
  5. Seiler S, Di Santo S, Andereggen L, Widmer H. ‌Antagonization of the Nogo-Receptor 1 Enhances Dopaminergic Fiber Outgrowth of Transplants in a Rat Model of Parkinson’s Disease Front Cell Neurosci. 2017 May 26;11:151.
  6. Seiler S, Di Santo S, Sahli S, Andereggen L, Widmer H. ‌Nogo-receptor 1 antagonization in combination with neurotrophin-4/5 is not superior to single factor treatment in promoting survival and morphological complexity of cultured dopaminergic neurons Brain Res. 2017 Aug 1;1668:56-64.
  7. Andereggen L, Widmer H, Di Santo S, Andres R. ‌Functional muscle strength recovery from nail gun injury to the primary motor cortex. Regen Med. 2020 May;15(5):1603-1609.
  8. Wanderer S, Grüter B, Strange F, Sivanrupan S, Di Santo S, Widmer H, Fandino J, Marbacher S, Andereggen L. ‌The Role of Sartans in the Treatment of Stroke and Subarachnoid Hemorrhage: A Narrative Review of Preclinical and Clinical Studies. Brain Sci. 2020 Mar 7;10(3):153.
  9. Di Santo S, Seiler S, Guzman R, Widmer H. ‌Endothelial Progenitor Cell-Derived Factors Exert Neuroprotection in Cultured Cortical Neuronal Progenitor Cells. Cell Transplant. Jan-Dec 2020;29:963689720912689.
  10. Di Santo S, Seiler S, Ducray A, Widmer H. ‌Conditioned medium from Endothelial Progenitor Cells promotes number of dopaminergic neurons and exerts neuroprotection in cultured ventral mesencephalic neuronal progenitor cells. Brain Res. 2019 Oct 1;1720:146330.
  11. Croci D, Wanderer S, Strange F, Grüter B, Casoni D, Sivanrupan S, Widmer H, Di Santo S, Fandino J, Mariani L, Marbacher S. ‌Systemic and CSF Interleukin-1α Expression in a Rabbit Closed Cranium Subarachnoid Hemorrhage Model: An Exploratory Study. Brain Sci. 2019 Sep 24;9(10):249.
  12. Grüter B, Wanderer S, Strange F, Boillat G, Täschler D, Rey J, Croci D, Grandgirard D, Leib S, von Gunten M, Di Santo S, Widmer H, Remonda L, Andereggen L, Nevzati E, Coluccia D, Fandino J, Marbacher S. ‌Patterns of Neointima Formation After Coil or Stent Treatment in a Rat Saccular Sidewall Aneurysm Model Stroke. 2021 Mar;52(3):1043-1052
  13. Widmer H, Di Santo S. ‌Current Perspectives on Neurological Diseases: Experimental Models, Mechanisms of Disease and Treatments CNS Neurol Disord Drug Targets . 2020;19(8):558-559.
  14. Sadanandan N, Di Santo S, Widmer H. ‌Another win for endothelial progenitor cells: Endothelial progenitor cell-derived conditioned medium promotes proliferation and exerts neuroprotection in cultured neuronal progenitor cells Brain Circ. 2019 Sep 30;5(3):106-111.
  15. Di Santo S, Meyer M, Ducray A, Andereggen L, Widmer H. ‌A Combination of NT-4/5 and GDNF Is Favorable for Cultured Human Nigral Neural Progenitor Cells Cell Transplant. 2018 Apr;27(4):648-653.
  16. Andereggen L, Reitmeir R, Di Santo S, Guzman R, Widmer H, Marbacher S, Andres R. ‌Modulation of Post-Stroke Plasticity and Regeneration by Stem Cell Therapy and Exogenic Factors In: Lapchak P., Zhang J. (eds) Cellular and Molecular Approaches to Regeneration and Repair. Springer Series in Translational Stroke Research. Springer, Cham. 2017;129-152.
  17. Di Santo S, Widmer H. ‌Neurotrophic factor-based strategies to enhance survival and differentiation of neural progenitor cells toward the dopaminergic phenotype Brain Circ. Jul-Sep 2018;4(3):139-141.
  18. Perez-Bouza A, Di Santo S, Seiler S, Meyer M, Andereggen L, Huber A, Guzman R, Widmer H. ‌Simultaneous Transplantation of Fetal Ventral Mesencephalic Tissue and Encapsulated Genetically Modified Cells Releasing GDNF in a Hemi-Parkinsonian Rat Model of Parkinson’s Disease Cell Transplant. 2017 Sep;26(9):1572-1581.
  19. Yang Z, Di Santo S, Kalka C. ‌Current developments in the use of stem cell for therapeutic neovascularisation: is the future therapy “cell-free”? Swiss Med Wkly. 2010 Dec 17;140:w13130.